The Science Behind Cannabis Quality Loss in Transit

Cannabis transportation management professionals recognize that shipping times and delays play a pivotal role in preserving product quality. Extending transit time raises risks that compromise the integrity of cannabinoids, terpenes, and overall consumer experience.


Temperature and Terpene Loss

Terpenes—volatile aromatic compounds—are acutely sensitive to temperature fluctuations. Many begin degrading at temperatures as low as 70 °F and more aggressively around 100 °F. During prolonged transit, especially in summer or unconditioned storage, these compounds can evaporate or break down. This not only diminishes flavor and aroma but also undermines the “entourage effect,” the synergistic relationship between terpenes and cannabinoids.


Humidity, Oxidation, and Mold Development

Inadequate packaging or poor environmental controls in transit can expose cannabis to humidity swings and air. Excess moisture promotes mold growth, while low humidity causes drying and brittleness. Oxygen exposure accelerates cannabinoid oxidation, reducing THC and CBD potency over time.


Cannabinoid Degradation Kinetics

Scientific analyses show that THC decarboxylates and degrades over time; in resin and extracts, 50% potency loss may occur in ~35 days if stored at room temperature with sunlight exposure. Even in darkness, cannabinoid half-lives remain finite (~462 days), meaning that any shipment delays erode value and therapeutic efficacy.


High-Terpene Extracts (HTE) Are Fragile

HTE products—rich in terpenes—face even greater instability. In controlled testing, 87% of HTE formulations exhibited significant sensory degradation within 60–90 days—even with ideal packaging. This underscores the necessity for rapid and refrigerated shipping of terpene-rich products.


Logistical Considerations: Cold Chain & Packaging Systems

Modern cannabis supply chains often borrow strategies from pharmaceuticals, using cold-chain or insulated systems with dry ice or gel packs to maintain stable temperatures. Passive systems may offer several days of thermal protection—critical for transit in extreme heat. Regular temperature monitoring further ensures compliance with GxP and QC standards.


Packaging Integrity and Testing

Robust packaging must resist punctures, UV light, oxygen, and humidity. Industry best practices involve stress testing containers for vibration, thermal shifts, and shock to confirm their resilience. Specialized bags and opaque containers fortified with humidity buffers preserve freshness.


Operational Implications

Shipping delays not only degrade product chemistry but also diminish consumer trust and brand reputation. Re-testing due to failed quality checks incurs costs, and subpar products encourage returns or complaints. Efficient logistics, cold-chain infrastructure, and quality packaging thus represent vital investments in risk mitigation.


In Review

Extended shipping times, temperature variability, and suboptimal packaging are key risk factors in the degradation of cannabis potency, flavor, and safety. Transportation managers must prioritize:

  • Controlled-temperature shipping—including cold chain or insulated systems
  • Validated packaging solutions tested for physical and environmental stress
  • Proactive monitoring of transit conditions
  • Rapid dispatch protocols to minimise total elapsed time

By integrating these strategies into logistics operations, the industry can ensure that products arrive fresh, potent, and compliant—protecting both consumer safety and brand integrity.